Research Articles
Unlocking New Cancer Therapy: Targeting Protein Destruction in p53-Deficient Tumors
Discover how b-AP15 inhibition of USP14 and UCH37 deubiquitinating activity offers potential therapy for tumors with p53 deficiency
Taming the Guardian's Jailer: A New Weapon in the Fight Against Cancer
Explore the revolutionary approach of targeted MDM2 degradation using PROTACs as a novel cancer therapy that destroys cancer-causing proteins rather than just inhibiting them.
Metal Warriors: The Double-Edged Sword of Heavy Metal Complexes in Cancer Therapy
Exploring the anticancer potential and neurotoxicity challenges of novel heavy metal-based complexes in cancer treatment
Disaster in the Cancer Cell: Sabotaging the Cell's Emergency Crew
How scientists are exploiting the chaos inside cancer cells by targeting Heat Shock Proteins and the Proteasome to create powerful new treatments.
Breaking Cancer's Defenses: How Scientists Are Targeting Treatment-Resistant Tumors
Discover how QLS1209, a novel PKMYT1 inhibitor, is revolutionizing cancer treatment through synthetic lethality targeting CCNE1-amplified and FBXW7-mutated tumors.